Last Updated on November 17, 2022 2:14 pm by Erwin Noguera
The 2022-23 NFL season closes its annual series of international games this Week 11, when the Arizona Cardinals and San Francisco 49ers head to Mexico City, specifically to Estadio Azteca, for this week’s Monday Night Football game.
The NFL is back in Mexican territory after two years of absence, after the suspension in two consecutive years of this tour in the neighboring country due to the Covid-19 pandemic and, despite being on World Cup dates, this event will not go unnoticed by NFL fans in Mexico.
This will be the fifth game to be played at the Azteca Stadium in the history of the league, and the match-up between the San Francisco 49ers and the Arizona Cardinals will be the first to be repeated in Mexico, as both played in Mexican territory in the 2005 season.
The Cardinals will be the administrative home for this game because their stadium, State Farm Stadium, is the site of the upcoming Super Bowl LVII, which is why they had to give up one of their nine home games in the current season to have the “big game”.
Monday Night Football – Arizona Cardinals vs. San Francisco 49ers – Betting Odds & Free Pick – Info
Monday, November 21 at 08:15 pm ET at the Azteca Stadium in México City
Where Can I Watch it?
Why Bet on the Cardinals
The Arizona Cardinals have not had the first half of the season they would have dreamed of, especially in their home games, as they have a terrible 1-4 record and, even though this game will be in Mexico, the Cardinals will be as the local.
The Cardinals, in a battle of starting backup quarterbacks in place of injured starters, defeated the Los Angeles Rams 27-17 on Sunday as visitors.
The Cardinals are led by quarterback Kyler Murray and defensive wing J.J. Watt. Murray is unlikely to be available for this game, so hopes are pinned on Colt McCoy and Trace McSorley, who are the backup quarterbacks and will have the difficult task of commanding their team’s offense.
On the other hand, we have receivers Marquise Brown and Rondale Moore, both with a great season averaging 10.7 yards on 42 interceptions and 4 touchdowns between them.
Why Bet on the 49ers
On the other hand, we have the San Francisco 49ers, a team that has had a season with ups and downs, but they have managed to maintain a positive record during almost the entire season, in addition, they should take advantage of the fact that in the NFC West, there is no team escaping at the top of the table, so if they continue with the winning streak they could climb and take over the first place.
The 49ers are considered a playoff contender because they have a star-studded roster led by quarterback Jimmy Garoppolo, wide receiver Deebo Samuel, and defensive end Nick Bosa.
Garappolo has a great pass completion percentage of 66.8% coming on 159/238 passing for 1,931 yards, 11 touchdowns, and 4 interceptions. Samuel has 34 receptions for 411 yards and 2 touchdowns. While Bosa is the defensive player that gives the team the most security.
San Francisco comes into this game after a big win at home against the Los Angeles Chargers with a score of 22-16.
Final Betting Analysis: Arizona Cardinals vs San Francisco 49ers
The Cardinals and 49ers have met 61 times in league history. The 49ers lead the series with a 32-29 record, although the Cardinals have won 3 of the last 4 meetings and are 11-3 against the 49ers since the 2015 season.
At MyBookie.ag we can see that there is a Moneyline that favors the San Francisco 49ers at -359, while Arizona Cardinals start at +275.
The confidence level of the 49ers should be high after winning back-to-back games against the Rams and Chargers.
That is why our pick for this game is the San Francisco 49ers win and, in addition, we suggest the SPREAD on the 49ers at -8 and the Over 43.5.
Look for a straight win on the Moneyline San Francisco 49ers. If you put $100 on the 49ers at -359, you’ll be looking at a $27.88 win with a total payout of $127.88.